Price: $94.90 - $54.95
(as of Mar 25, 2023 07:39:01 UTC – Details)
Product Description
OsetoPhase contains a unique, naturally rich source of calcium along with time-proven osteo-supportive herbs and botanicals, including:
Concha Ostrea: Concha Ostrea oyster shell, or Ostrea talienwhanensis shell, provides calcium carbonate, along with additional minerals, glycolipids and nutrients. Ostrea is widely used in traditional Chinese practice. Studies have shown that this unique source of calcium may support bone-building. (1), (2) Astragalus Polysaccharides: Known to support healthy, oxygen-rich microcirculation, extracts of Astragalus have also been shown to promote bone health in laboratory animals. (3) Angelica Sinensis: Angelica has been shown to stimulate the proliferation of precursor cells to maintain bone health. (4) Coix Seed: Long used in traditional Chinese healing, and as a food, Coix seeds have been shown to support bone health. (5)
References
1. BMC Complement Altern Med. 2014 Dec 12;14:481 Angelica sinensis extract inhibits RANKL-mediated osteoclastogenesis by down-regulated the expression of NFATc1 in mouse bone marrow cells. Kong L, Zhao Q, Wang X, Zhu J, Hao D, Yang C.
2. Br J Pharmacol. 2018 Mar;175(6):902-923. Tanshinones that selectively block the collagenase activity of cathepsin K provide a novel class of ectosteric antiresorptive agents for bone. Panwar P, Law S, Jamroz A, Azizi P, Zhang D, Ciufolini M, Bromme D.
3. Int J Mol Sci. 2016 Dec 16;17(12). Discovery of a New Class of Cathepsin K Inhibitors in Rhizoma Drynariae as Potential Candidates for the Treatment of Osteoporosis. Qiu ZC, D. XL, Dai Y, Xiao GK, Wang XL, Wong KC, Wong MS, Yao XS.
4. J Ethnopharmacol. 2014 Apr 28. Effects of total lignans from Eucommia ulmoides barks prevent bone loss in vivo and in vitro. Zhang R, Pan YL, Hu SG, Kong XH, Juan W, Mei Q.
5. Phytother Res. 2016 Oct;30(10):1680-1688. Astragaloside I Stimulates Osteoblast Differentiation Through the Wnt/β-catenin Signaling Pathway. Cheng X, Wei B, Sun L, Hu X, Liang J, Chen Y.
6. Chem Biol Interact. 2018 Mar 1:283:51-58. Involvement of bone morphogenetic protein-related pathways in the effect of aucubin on the promotion of osteoblast differentiation in MG63 cells. Li Y, Hu W, Han G, Lu W, Jia D, Hu M, Wang D.
7. Phytother Res. 2014 Jan;28(1):1-8. The role of traditional Chinese medicines in osteogenesis and angiogenesis. Yang Y, Chin A, Zhang L, Lu J, Wong RW.
Is Discontinued By Manufacturer : No
Package Dimensions : 4.29 x 2.4 x 2.28 inches; 3.21 Ounces
Date First Available : February 19, 2014
Manufacturer : Tango Advanced Nutrition
ASIN : B00IJJKXPG
Country of Origin : USA
Regulates how your body uses calcium and other nutrients for bone structure
Improves blood circulation to and within skeletal bones
Assists in maintaining bone density and strength